Adaptation of antibiotic treatment to clinical practice guidelines in patients aged ⩾65 years hospitalised due to community-acquired pneumonia.
Identifieur interne : 000081 ( Main/Exploration ); précédent : 000080; suivant : 000082Adaptation of antibiotic treatment to clinical practice guidelines in patients aged ⩾65 years hospitalised due to community-acquired pneumonia.
Auteurs : M A Fernandez-Sierra [Espagne] ; M T Rueda-Domingo [Espagne] ; M M Rodriguez-Del-Aguila [Espagne] ; M J Perez-Lozano [Espagne] ; L. Force [Espagne] ; T. Fernandez-Villa [Espagne] ; J. Astray [Espagne] ; M. Egurrola [Espagne] ; J. Castilla [Espagne] ; F. Sanz [Espagne] ; D. Toledo [Espagne] ; A. Dominguez [Espagne]Source :
- Epidemiology and infection [ 1469-4409 ] ; 2018.
Descripteurs français
- KwdFr :
- Antibactériens (usage thérapeutique), Espagne (MeSH), Femelle (MeSH), Guides de bonnes pratiques cliniques comme sujet (MeSH), Hospitalisation (statistiques et données numériques), Humains (MeSH), Infections communautaires (traitement médicamenteux), Modèles logistiques (MeSH), Mâle (MeSH), Pneumopathie infectieuse (traitement médicamenteux), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Unités de soins intensifs (statistiques et données numériques).
- MESH :
- statistiques et données numériques : Hospitalisation, Unités de soins intensifs.
- traitement médicamenteux : Infections communautaires, Pneumopathie infectieuse.
- usage thérapeutique : Antibactériens.
- Espagne, Femelle, Guides de bonnes pratiques cliniques comme sujet, Humains, Modèles logistiques, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus.
- Wicri :
- geographic : Espagne.
English descriptors
- KwdEn :
- Aged (MeSH), Aged, 80 and over (MeSH), Anti-Bacterial Agents (therapeutic use), Community-Acquired Infections (drug therapy), Female (MeSH), Hospitalization (statistics & numerical data), Humans (MeSH), Intensive Care Units (statistics & numerical data), Logistic Models (MeSH), Male (MeSH), Pneumonia (drug therapy), Practice Guidelines as Topic (MeSH), Spain (MeSH).
- MESH :
- chemical , therapeutic use : Anti-Bacterial Agents.
- geographic : Spain.
- drug therapy : Community-Acquired Infections, Pneumonia.
- statistics & numerical data : Hospitalization, Intensive Care Units.
- Aged, Aged, 80 and over, Female, Humans, Logistic Models, Male, Practice Guidelines as Topic.
Abstract
Early, conforming antibiotic treatment in elderly patients hospitalised for community-acquired pneumonia (CAP) is a key factor in the prognosis and mortality. The objective was to examine whether empirical antibiotic treatment was conforming according to the Spanish Society of Pulmonology and Thoracic Surgery guidelines in these patients. Multicentre study in patients aged ⩾65 years hospitalised due to CAP in the 2013-14 and 2014-15 influenza seasons. We collected socio-demographic information, comorbidities, influenza/pneumococcal vaccination history and antibiotics administered using a questionnaire and medical records. Bivariate analyses and multilevel logistic regression were made. In total, 1857 hospitalised patients were included, 82 of whom required intensive care unit (ICU) admission. Treatment was conforming in 51.4% (95% confidence interval (CI) 49.1-53.8%) of patients without ICU admission and was associated with absence of renal failure without haemodialysis (odds ratio (OR) 1.49, 95% CI 1.15-1.95) and no cognitive dysfunction (OR 1.71, 95% CI 1.25-2.35), when the effect of the autonomous community was controlled for. In patients with ICU admission, treatment was conforming in 45.1% (95% CI 34.1-56.1%) of patients and was associated with the hospital visits in the last year (<3 vs. ⩾3, OR 2.70, 95% CI 1.03-7.12) and there was some evidence that this was associated with season. Although the reference guidelines are national, wide variability between autonomous communities was found. In patients hospitalised due to CAP, health services should guarantee the administration of antibiotics in a consensual manner that is conforming according to clinical practice guidelines.
DOI: 10.1017/S0950268818002121
PubMed: 30070190
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Force</name><affiliation wicri:level="3"><nlm:affiliation>Hospital de Mataró,Barcelona,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital de Mataró,Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Fernandez Villa, T" sort="Fernandez Villa, T" uniqKey="Fernandez Villa T" first="T" last="Fernandez-Villa">T. Fernandez-Villa</name><affiliation wicri:level="1"><nlm:affiliation>Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS). Instituto de Biomedicina (IBIOMED). Universidad de León,León,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS). Instituto de Biomedicina (IBIOMED). 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Egurrola</name><affiliation wicri:level="1"><nlm:affiliation>Hospital de Galdakao, Usansolo,Vizcaya,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital de Galdakao, Usansolo,Vizcaya</wicri:regionArea><wicri:noRegion>Vizcaya</wicri:noRegion></affiliation></author><author><name sortKey="Castilla, J" sort="Castilla, J" uniqKey="Castilla J" first="J" last="Castilla">J. Castilla</name><affiliation wicri:level="1"><nlm:affiliation>Instituto de Salud Pública de Navarra, IdiSNA,Pamplona,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Instituto de Salud Pública de Navarra, IdiSNA,Pamplona</wicri:regionArea><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Sanz, F" sort="Sanz, F" uniqKey="Sanz F" first="F" last="Sanz">F. Sanz</name><affiliation wicri:level="1"><nlm:affiliation>Consorci Hospital General Universitari de Valencia,Valencia,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Consorci Hospital General Universitari de Valencia,Valencia</wicri:regionArea><wicri:noRegion>Valencia</wicri:noRegion></affiliation></author><author><name sortKey="Toledo, D" sort="Toledo, D" uniqKey="Toledo D" first="D" last="Toledo">D. Toledo</name><affiliation wicri:level="3"><nlm:affiliation>CIBER Epidemiología y Salud Pública (CIBERESP),Madrid,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER Epidemiología y Salud Pública (CIBERESP),Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Dominguez, A" sort="Dominguez, A" uniqKey="Dominguez A" first="A" last="Dominguez">A. 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Hospital Universitario Virgen de las Nieves,Granada,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>UGC Prevención Promoción y Vigilancia Salud. Hospital Universitario Virgen de las Nieves,Granada</wicri:regionArea><wicri:noRegion>Granada</wicri:noRegion></affiliation></author><author><name sortKey="Rueda Domingo, M T" sort="Rueda Domingo, M T" uniqKey="Rueda Domingo M" first="M T" last="Rueda-Domingo">M T Rueda-Domingo</name><affiliation wicri:level="1"><nlm:affiliation>UGC Prevención Promoción y Vigilancia Salud. Hospital Universitario Virgen de las Nieves,Granada,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>UGC Prevención Promoción y Vigilancia Salud. Hospital Universitario Virgen de las Nieves,Granada</wicri:regionArea><wicri:noRegion>Granada</wicri:noRegion></affiliation></author><author><name sortKey="Rodriguez Del Aguila, M M" sort="Rodriguez Del Aguila, M M" uniqKey="Rodriguez Del Aguila M" first="M M" last="Rodriguez-Del-Aguila">M M Rodriguez-Del-Aguila</name><affiliation wicri:level="1"><nlm:affiliation>UGC Prevención Promoción y Vigilancia Salud. Hospital Universitario Virgen de las Nieves,Granada,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>UGC Prevención Promoción y Vigilancia Salud. Hospital Universitario Virgen de las Nieves,Granada</wicri:regionArea><wicri:noRegion>Granada</wicri:noRegion></affiliation></author><author><name sortKey="Perez Lozano, M J" sort="Perez Lozano, M J" uniqKey="Perez Lozano M" first="M J" last="Perez-Lozano">M J Perez-Lozano</name><affiliation wicri:level="1"><nlm:affiliation>UGC Prevención,Promoción y Vigilancia Salud. Hospital de Valme,Sevilla,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>UGC Prevención,Promoción y Vigilancia Salud. Hospital de Valme,Sevilla</wicri:regionArea><wicri:noRegion>Sevilla</wicri:noRegion></affiliation></author><author><name sortKey="Force, L" sort="Force, L" uniqKey="Force L" first="L" last="Force">L. Force</name><affiliation wicri:level="3"><nlm:affiliation>Hospital de Mataró,Barcelona,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital de Mataró,Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Fernandez Villa, T" sort="Fernandez Villa, T" uniqKey="Fernandez Villa T" first="T" last="Fernandez-Villa">T. Fernandez-Villa</name><affiliation wicri:level="1"><nlm:affiliation>Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS). Instituto de Biomedicina (IBIOMED). Universidad de León,León,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS). Instituto de Biomedicina (IBIOMED). Universidad de León,León</wicri:regionArea><wicri:noRegion>León</wicri:noRegion></affiliation></author><author><name sortKey="Astray, J" sort="Astray, J" uniqKey="Astray J" first="J" last="Astray">J. Astray</name><affiliation wicri:level="3"><nlm:affiliation>Consejería de Sanidad de Madrid,Madrid,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Consejería de Sanidad de Madrid,Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Egurrola, M" sort="Egurrola, M" uniqKey="Egurrola M" first="M" last="Egurrola">M. Egurrola</name><affiliation wicri:level="1"><nlm:affiliation>Hospital de Galdakao, Usansolo,Vizcaya,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Hospital de Galdakao, Usansolo,Vizcaya</wicri:regionArea><wicri:noRegion>Vizcaya</wicri:noRegion></affiliation></author><author><name sortKey="Castilla, J" sort="Castilla, J" uniqKey="Castilla J" first="J" last="Castilla">J. Castilla</name><affiliation wicri:level="1"><nlm:affiliation>Instituto de Salud Pública de Navarra, IdiSNA,Pamplona,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Instituto de Salud Pública de Navarra, IdiSNA,Pamplona</wicri:regionArea><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Sanz, F" sort="Sanz, F" uniqKey="Sanz F" first="F" last="Sanz">F. Sanz</name><affiliation wicri:level="1"><nlm:affiliation>Consorci Hospital General Universitari de Valencia,Valencia,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Consorci Hospital General Universitari de Valencia,Valencia</wicri:regionArea><wicri:noRegion>Valencia</wicri:noRegion></affiliation></author><author><name sortKey="Toledo, D" sort="Toledo, D" uniqKey="Toledo D" first="D" last="Toledo">D. Toledo</name><affiliation wicri:level="3"><nlm:affiliation>CIBER Epidemiología y Salud Pública (CIBERESP),Madrid,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER Epidemiología y Salud Pública (CIBERESP),Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Dominguez, A" sort="Dominguez, A" uniqKey="Dominguez A" first="A" last="Dominguez">A. Dominguez</name><affiliation wicri:level="3"><nlm:affiliation>CIBER Epidemiología y Salud Pública (CIBERESP),Madrid,Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER Epidemiología y Salud Pública (CIBERESP),Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author></analytic><series><title level="j">Epidemiology and infection</title><idno type="eISSN">1469-4409</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Anti-Bacterial Agents (therapeutic use)</term><term>Community-Acquired Infections (drug therapy)</term><term>Female (MeSH)</term><term>Hospitalization (statistics & numerical data)</term><term>Humans (MeSH)</term><term>Intensive Care Units (statistics & numerical data)</term><term>Logistic Models (MeSH)</term><term>Male (MeSH)</term><term>Pneumonia (drug therapy)</term><term>Practice Guidelines as Topic (MeSH)</term><term>Spain (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Antibactériens (usage thérapeutique)</term><term>Espagne (MeSH)</term><term>Femelle (MeSH)</term><term>Guides de bonnes pratiques cliniques comme sujet (MeSH)</term><term>Hospitalisation (statistiques et données numériques)</term><term>Humains (MeSH)</term><term>Infections communautaires (traitement médicamenteux)</term><term>Modèles logistiques (MeSH)</term><term>Mâle (MeSH)</term><term>Pneumopathie infectieuse (traitement médicamenteux)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Unités de soins intensifs (statistiques et données numériques)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Bacterial Agents</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Spain</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Community-Acquired Infections</term><term>Pneumonia</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term><term>Intensive Care Units</term></keywords><keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Hospitalisation</term><term>Unités de soins intensifs</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections communautaires</term><term>Pneumopathie infectieuse</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antibactériens</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Humans</term><term>Logistic Models</term><term>Male</term><term>Practice Guidelines as Topic</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Espagne</term><term>Femelle</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Modèles logistiques</term><term>Mâle</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Early, conforming antibiotic treatment in elderly patients hospitalised for community-acquired pneumonia (CAP) is a key factor in the prognosis and mortality. The objective was to examine whether empirical antibiotic treatment was conforming according to the Spanish Society of Pulmonology and Thoracic Surgery guidelines in these patients. Multicentre study in patients aged ⩾65 years hospitalised due to CAP in the 2013-14 and 2014-15 influenza seasons. We collected socio-demographic information, comorbidities, influenza/pneumococcal vaccination history and antibiotics administered using a questionnaire and medical records. Bivariate analyses and multilevel logistic regression were made. In total, 1857 hospitalised patients were included, 82 of whom required intensive care unit (ICU) admission. Treatment was conforming in 51.4% (95% confidence interval (CI) 49.1-53.8%) of patients without ICU admission and was associated with absence of renal failure without haemodialysis (odds ratio (OR) 1.49, 95% CI 1.15-1.95) and no cognitive dysfunction (OR 1.71, 95% CI 1.25-2.35), when the effect of the autonomous community was controlled for. In patients with ICU admission, treatment was conforming in 45.1% (95% CI 34.1-56.1%) of patients and was associated with the hospital visits in the last year (<3 vs. ⩾3, OR 2.70, 95% CI 1.03-7.12) and there was some evidence that this was associated with season. Although the reference guidelines are national, wide variability between autonomous communities was found. In patients hospitalised due to CAP, health services should guarantee the administration of antibiotics in a consensual manner that is conforming according to clinical practice guidelines.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30070190</PMID><DateCompleted><Year>2019</Year><Month>05</Month><Day>09</Day></DateCompleted><DateRevised><Year>2019</Year><Month>05</Month><Day>09</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1469-4409</ISSN><JournalIssue CitedMedium="Internet"><Volume>146</Volume><Issue>14</Issue><PubDate><Year>2018</Year><Month>10</Month></PubDate></JournalIssue><Title>Epidemiology and infection</Title><ISOAbbreviation>Epidemiol. Infect.</ISOAbbreviation></Journal><ArticleTitle>Adaptation of antibiotic treatment to clinical practice guidelines in patients aged ⩾65 years hospitalised due to community-acquired pneumonia.</ArticleTitle><Pagination><MedlinePgn>1870-1877</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1017/S0950268818002121</ELocationID><Abstract><AbstractText>Early, conforming antibiotic treatment in elderly patients hospitalised for community-acquired pneumonia (CAP) is a key factor in the prognosis and mortality. The objective was to examine whether empirical antibiotic treatment was conforming according to the Spanish Society of Pulmonology and Thoracic Surgery guidelines in these patients. Multicentre study in patients aged ⩾65 years hospitalised due to CAP in the 2013-14 and 2014-15 influenza seasons. We collected socio-demographic information, comorbidities, influenza/pneumococcal vaccination history and antibiotics administered using a questionnaire and medical records. Bivariate analyses and multilevel logistic regression were made. In total, 1857 hospitalised patients were included, 82 of whom required intensive care unit (ICU) admission. Treatment was conforming in 51.4% (95% confidence interval (CI) 49.1-53.8%) of patients without ICU admission and was associated with absence of renal failure without haemodialysis (odds ratio (OR) 1.49, 95% CI 1.15-1.95) and no cognitive dysfunction (OR 1.71, 95% CI 1.25-2.35), when the effect of the autonomous community was controlled for. In patients with ICU admission, treatment was conforming in 45.1% (95% CI 34.1-56.1%) of patients and was associated with the hospital visits in the last year (<3 vs. ⩾3, OR 2.70, 95% CI 1.03-7.12) and there was some evidence that this was associated with season. Although the reference guidelines are national, wide variability between autonomous communities was found. In patients hospitalised due to CAP, health services should guarantee the administration of antibiotics in a consensual manner that is conforming according to clinical practice guidelines.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Fernandez-Sierra</LastName><ForeName>M A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>UGC Prevención Promoción y Vigilancia Salud. Hospital Universitario Virgen de las Nieves,Granada,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rueda-Domingo</LastName><ForeName>M T</ForeName><Initials>MT</Initials><AffiliationInfo><Affiliation>UGC Prevención Promoción y Vigilancia Salud. Hospital Universitario Virgen de las Nieves,Granada,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rodriguez-Del-Aguila</LastName><ForeName>M M</ForeName><Initials>MM</Initials><Identifier Source="ORCID">0000-0002-6933-1102</Identifier><AffiliationInfo><Affiliation>UGC Prevención Promoción y Vigilancia Salud. Hospital Universitario Virgen de las Nieves,Granada,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Perez-Lozano</LastName><ForeName>M J</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>UGC Prevención,Promoción y Vigilancia Salud. Hospital de Valme,Sevilla,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Force</LastName><ForeName>L</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Hospital de Mataró,Barcelona,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fernandez-Villa</LastName><ForeName>T</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Grupo de Investigación en Interacciones Gen-Ambiente y Salud (GIIGAS). Instituto de Biomedicina (IBIOMED). Universidad de León,León,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Astray</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Consejería de Sanidad de Madrid,Madrid,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Egurrola</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Hospital de Galdakao, Usansolo,Vizcaya,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Castilla</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Instituto de Salud Pública de Navarra, IdiSNA,Pamplona,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sanz</LastName><ForeName>F</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Consorci Hospital General Universitari de Valencia,Valencia,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Toledo</LastName><ForeName>D</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>CIBER Epidemiología y Salud Pública (CIBERESP),Madrid,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dominguez</LastName><ForeName>A</ForeName><Initials>A</Initials><Identifier Source="ORCID">0000-0003-0219-1907</Identifier><AffiliationInfo><Affiliation>CIBER Epidemiología y Salud Pública (CIBERESP),Madrid,Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>Workgroup Project PI12/02079</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>08</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Epidemiol Infect</MedlineTA><NlmUniqueID>8703737</NlmUniqueID><ISSNLinking>0950-2688</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017714" MajorTopicYN="N">Community-Acquired Infections</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007362" MajorTopicYN="N">Intensive Care Units</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016015" MajorTopicYN="N">Logistic Models</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011014" MajorTopicYN="N">Pneumonia</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017410" MajorTopicYN="Y">Practice Guidelines as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Antibiotic treatment</Keyword><Keyword MajorTopicYN="Y">community-acquired pneumonia</Keyword><Keyword MajorTopicYN="Y">correctness</Keyword><Keyword MajorTopicYN="Y">elderly</Keyword><Keyword MajorTopicYN="Y">hospital</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>8</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>5</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>8</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">30070190</ArticleId><ArticleId IdType="pii">S0950268818002121</ArticleId><ArticleId IdType="doi">10.1017/S0950268818002121</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Espagne</li></country><region><li>Catalogne</li><li>Communauté de Madrid</li></region><settlement><li>Barcelone</li><li>Madrid</li></settlement></list><tree><country name="Espagne"><noRegion><name sortKey="Fernandez Sierra, M A" sort="Fernandez Sierra, M A" uniqKey="Fernandez Sierra M" first="M A" last="Fernandez-Sierra">M A Fernandez-Sierra</name></noRegion><name sortKey="Astray, J" sort="Astray, J" uniqKey="Astray J" first="J" last="Astray">J. Astray</name><name sortKey="Castilla, J" sort="Castilla, J" uniqKey="Castilla J" first="J" last="Castilla">J. Castilla</name><name sortKey="Dominguez, A" sort="Dominguez, A" uniqKey="Dominguez A" first="A" last="Dominguez">A. Dominguez</name><name sortKey="Egurrola, M" sort="Egurrola, M" uniqKey="Egurrola M" first="M" last="Egurrola">M. Egurrola</name><name sortKey="Fernandez Villa, T" sort="Fernandez Villa, T" uniqKey="Fernandez Villa T" first="T" last="Fernandez-Villa">T. Fernandez-Villa</name><name sortKey="Force, L" sort="Force, L" uniqKey="Force L" first="L" last="Force">L. Force</name><name sortKey="Perez Lozano, M J" sort="Perez Lozano, M J" uniqKey="Perez Lozano M" first="M J" last="Perez-Lozano">M J Perez-Lozano</name><name sortKey="Rodriguez Del Aguila, M M" sort="Rodriguez Del Aguila, M M" uniqKey="Rodriguez Del Aguila M" first="M M" last="Rodriguez-Del-Aguila">M M Rodriguez-Del-Aguila</name><name sortKey="Rueda Domingo, M T" sort="Rueda Domingo, M T" uniqKey="Rueda Domingo M" first="M T" last="Rueda-Domingo">M T Rueda-Domingo</name><name sortKey="Sanz, F" sort="Sanz, F" uniqKey="Sanz F" first="F" last="Sanz">F. Sanz</name><name sortKey="Toledo, D" sort="Toledo, D" uniqKey="Toledo D" first="D" last="Toledo">D. Toledo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|wiki= Sante
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|texte= Adaptation of antibiotic treatment to clinical practice guidelines in patients aged ⩾65 years hospitalised due to community-acquired pneumonia.
}}
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